GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs10935120 | 1 | rs6800862 | chr3:134228628 | ANAPC13 | chr3:134196547-134204865:- | 0.37 | 11.71 | 4.87E-28 | Height |
| THCA | cis | rs10935120 | 1 | rs6800862 | chr3:134228628 | CEP63 | chr3:134204575-134293852:+ | 0.29 | 6.38 | 4.28E-10 | Height |
| THCA | cis | rs9815925 | 1 | rs6801142 | chr3:184698444 | C3orf70 | chr3:184795840-184870802:- | -0.23 | -4.61 | 5.21E-6 | Heschl's gyrus morphology |
| THCA | cis | rs7219021 | 1 | rs68012338 | chr17:46856405 | CALCOCO2 | chr17:46908372-46942228:+ | -0.13 | -3.57 | 0.000393 | Schizophrenia or bipolar disorder |
| THCA | cis | rs7219021 | 1 | rs68012338 | chr17:46856405 | SNF8 | chr17:47007461-47022154:- | -0.22 | -6.74 | 4.47E-11 | Schizophrenia or bipolar disorder |
| THCA | cis | rs7219021 | 1 | rs68012338 | chr17:46856405 | UBE2Z | chr17:46985767-47006422:+ | -0.18 | -4.04 | 6.21E-5 | Schizophrenia or bipolar disorder |
| THCA | cis | rs11825709 | 1 | rs68012976 | chr11:93625796 | HEPHL1 | chr11:93754378-93847374:+ | 0.46 | 3.69 | 0.000253 | Obesity-related traits |
| THCA | cis | rs9815354 | 1 | rs6801343 | chr3:41767234 | ULK4 | chr3:41288091-42003660:- | 1.06 | 19.49 | 1.1E-62 | Diastolic blood pressure |
| THCA | cis | rs237743 | 1 | rs68014903 | chr20:47912039 | DDX27 | chr20:47835832-47860612:+ | 0.27 | 4.9 | 1.31E-6 | Height |
| THCA | cis | rs10935120 | 1 | rs6801596 | chr3:134252114 | ANAPC13 | chr3:134196547-134204865:- | 0.37 | 11.81 | 2.02E-28 | Height |
| THCA | cis | rs10935120 | 1 | rs6801596 | chr3:134252114 | CEP63 | chr3:134204575-134293852:+ | 0.3 | 6.54 | 1.6E-10 | Height |
| THCA | cis | rs11825709 | 1 | rs68019383 | chr11:93676398 | HEPHL1 | chr11:93754378-93847374:+ | 0.46 | 3.98 | 7.93E-5 | Obesity-related traits |
| THCA | cis | rs6797178 | 1 | rs6802109 | chr3:137250416 | NCK1 | chr3:136581073-136667967:+ | 0.13 | 3.51 | 0.000483 | Glucocorticoid-induced osteonecrosis |
| THCA | cis | rs6802315 | 1 | rs6802315 | chr3:158514360 | MFSD1 | chr3:158519912-158547504:+ | -0.14 | -3.74 | 0.000207 | Periodontitis (CDC/AAP) |
| THCA | cis | rs9815354 | 1 | rs6802340 | chr3:41894034 | ULK4 | chr3:41288091-42003660:- | 1.09 | 20.95 | 1.23E-69 | Diastolic blood pressure |